
Honoring 20 years of dedication from our team
This year, we had the privilege of celebrating 20 years of dedication from four of our esteemed colleagues—Sheila Guisado, Lourdes Gombau, Alberto Corcho, and Marta Corvo.
This year, we had the privilege of celebrating 20 years of dedication from four of our esteemed colleagues—Sheila Guisado, Lourdes Gombau, Alberto Corcho, and Marta Corvo.
Permeability assays are important for understanding how molecules cross biological barriers, assessing both their ability to cross and the mechanisms involved. While drugs are often absorbed by passive diffusion, some molecules can also be substrates for membrane proteins or transporters.
The permeability assay protocol for Caco-2 cells serves as a cornerstone in understanding and predicting the intestinal absorption of pharmaceutical agents.
This research, titled Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β‑Glucocerebrosidase, highlights the potential of fragment-based drug discovery (FBDD) and employs permeability assays with CacoReady and PreadyPort plates.