CacoGoblet

A mucus secreting ready-to-use concept for intestinal absorption evaluation

  • CacoGoblet, a mucus-secreting ready-to-use kit. The kit consists of 24 permeable supports seeded with differentiated polarized Caco-2 and human goblet cells. It allows in vitro intestinal absorption evaluation of drug targets in a barrier physiologically closer to the intestinal epithelium.
  • CacoGoblet is flexible, since plates can be used up to 5 days after ideal cell barrier differentation at day 21, being a time and cost-saving tool for early stage drug discovery and development.

CacoGoblet is a product manufactured in compliance with ISO 9001:2015

Applications

  • Evaluation of oral absorption efficiency, oral bioavailability and oral toxicity
  • Adaptation to High Throughput Screening of target compounds
  • Study of mechanisms involved in oral and intestinal absorption
  • Suitable for research on new delivery systems

Benefits

  • Available on demand
  • Ready-to-use without in-house cell line development or acquisition and cell propagation
  • More predictive model for compounds or formulations with passive diffusion transport pathway
  • Transportation and storage at room temperature in proprietary shipping medium
  • User friendly and easy-handling system
  • Adaptable to High Throughput automation

Product name – Reference

CacoGoblet 24 Transwell –  KRECE-CCG01
CacoGoblet 24 (individual transwell)  –  KRECE-CCG02

See also