News
Stay up-to-date on ReadyCell’s latest news, projects and developments.
Assessment of Drug Permeation across the Blood-Brain-Barrier (BBB) in preclinical research
The endothelial cells that conform the BBB limit the passage of blood circulating endogenous substrates and larger molecules to the brain. This intrinsic protective role is also a major hurdle for reasearchers developing drugs for Central Nervous System (CNS) disorders.
CacoReady in the literature
Evaluate intestinal inflammation with Caco2 cell-based in vitro kits to reproduce phisiological conditions.
Review of available cell-based in vitro models to evaluate intestinal permeability
Cell-based in vitro models are suitable to evaluate human phisiology optimizing research. This review introduce reference models to evaluate gastrointestinal metabolism.
ReadyCell visits FarmaForum
Our collaborators Carla Sapienza and Marta Ollé are attending Farmaforum Madrid to discuss last updates in pharmaceutical and cosmetics research.
Drug Drug interaction studies in preclinical stage, reduces unexpected adverse events rate in clinical trails
Specialized manufacturer of in vitro kits to evaluate uptake transporters, OCT2 and MATE1.
The evaluation of drug interactions in preclinical stages optimizes novel drug development
Specialized manufacturer of in vitro kits indicated to evaluate pharmacological relevant efflux and uptake receptors for TDI assays.
Role of pharmacological efflux receptors in cancer treatment resistance
Transmembrane efflux receptors, Pgp, MRP1 and BCRP has shown a relevant effect in the chemoterapy resistance.
Recommended cell-based in vitro testing to assess BCRP protein-mediated transport
PreadyPort BCRP is a in vitro system based on transfected MDCKII cells overexpressing the BCRP transporter.