Permeability Assays
Ready-to-use drug permeability kits will help you to ascertain your compound suitability for oral dosing.
Studying the permeability of compounds across a cell monolayer is a well-established in vitro technique to screen for oral absorption and evaluate transport mechanisms. Our range of pre-plated transwell products allows the rapid and accurate determination of drug transport across Caco-2 and MDCK II cell monolayers.
Your one-stop Caco-2 solution
24 or 96 transwell insert plates seeded with 21 days differentiated and polarized Caco-2 cells. The reference in vitro technique to evaluate intestinal permeability in novel orally administered compounds, according to leading regulatory agencies.
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| REFERENCE | DESCRIPTION | |
| KRECE-CCR01 | CacoReady 24 Transwell | |
| KRECE-CCR02 | CacoReady 24 Well (without transwell) | |
| KRECE-CCR04 | CacoReady 24 Well (individual transwell) | |
| KRECE-CCR50 | CacoReady 96 Transwell | |
| KRECE-CCR51 | CacoReady 96 Well (without transwell) |
CacoReady in the Literature
A secreting mucus intestinal barrier
24 transwell insert plates seeded with 21 days differentiated and polarized Caco-2 and HT-29 (human goblet) cells. An in vitro intestinal absorption evaluation of drug targets in a barrier physiologically closer to the intestinal epithelium.
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| REFERENCE | DESCRIPTION | |
| KRECE-CCG01 | CacoGoblet 24 Transwell | |
| KRECE-CCG02 | CacoGoblet 24 (individual transwell) |
CacoGoblet in the literature
An alternative cellular model based on MDCKII cells
24 and 96 transwell insert plates cultured with 12 days differentiated MDCKII parental line cells. A reference in vitro model to evaluate passive permeation and specific receptor mediated transport of new compounds.
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| REFERENCE | DESCRIPTION | |
| KRECE-CTR01 | PreadyPort-CTRL (24 Transwell) | |
| KRECE-CTR50 | PreadyPort-CTRL (96 Transwell) | |
| KRECE-MDR01 | PreadyPort-MDR1 (24 Transwell) | |
| KRECE-MDR02 | PreadyPort-MDR1/CTRL 1:1 (24 Transwell) | |
| KRECE-MDR50 | PreadyPort-MDR1 (96 Transwell) | |
| KRECE-MDR51 | PreadyPort-MDR1/CTRL 1:1 (96 Transwell) |
PreadyPort in the literature
ReadyCell ready-to-use cell monolayer kits benefits
- No in-house cell culture maintenance nor cell licensing costs
- Shipments worldwide to any location at room temperature thanks to our patented technology
- High flexibility
- High reproducibility within and between manufacturing batches
- Cell-based assays ready-to-use
- Highly predictive and useful in the in vitro to in vivo progression
- Technical support during the assay and in bio-analytics
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