PreadyPort BCRP

A novel ready-to-use system for in vitro drug transporter evaluation

  • PreadyPort BCRP is an in vitro model based in a differentiated MDCKII cell monolayer expressing BCRP on 96- or 24-well plates.
  • Monolayer assays using transfected MDCKII cells are widely recognized tools, recommended by the FDA, to study the interaction of drugs with efflux and/or uptake transporters.

PreadyPort BCRP is a product manufactured in compliance with ISO 9001:2015

Applications

  • BCRP substrate assessment for direct transport studies
  • BCRP inhibitor assessment for drug-drug interaction studies
  • Models the net transporter events of excretory cells and physiological barriers such as the human blood-brain barrier or the gastrointestinal tract and placenta

Benefits

  • Available on demand
  • Ready-to-use without in-house cell line development or acquisition and cell propagation
  • Transportation and storage at room temperature in proprietary shipping medium
  • User friendly and easy-handling system
  • High reproducibility
  • Adaptable to automation

Product name – Reference

PreadyPort-BCRP (24-Multiwell)  –  KRECE-BCP01
PreadyPort-BCRP/CTRL 1:1 (24-Multiwell)  –  KRECE-BCP02
PreadyPort-BCRP (96-Multiwell)  –  KRECE-BCP50
PreadyPort-BCRP/CTRL 1:1 (96-Multiwell)  –  KRECE-BCP51

PreadyPort-BCRP/CTRL Custom setup (96-Multiwell)  –  KRECE-BCP60

PreadyPort-CTRL (24-Multiwell)  –  KRECE-CTR01
PreadyPort-CTRL (96-Multiwell)  –  KRECE-CTR50

See also