PreadyPort MDR1

A ready-to-use tool for MDCKII-MDR1 monolayer assays

  • PreadyPort MDR1 is an in vitro model based in a differentiated MDCKII cell monolayer expressing MDR1 on 96- or 24-well plates.
  • Monolayer assays using transfected MDCKII cells are widely recognized tools, recommended by the FDA, to study the interaction of drugs with efflux and/or uptake transporters.

PreadyPort MDR1 is a product manufactured in compliance with ISO 9001:2015

Applications

  • MDR1 substrate assessment for direct transport studies
  • MDR1 inhibitor assessment for drug-drug interaction studies
  • Models the net transporter events of excretory cells and physiological barriers such as the human blood-brain barrier or the gastrointestinal tract and placenta

Benefits

  • Available on demand
  • Ready-to-use without in-house cell line development or acquisition and cell propagation
  • Transportation and storage at room temperature in proprietary shipping medium
  • User friendly and easy-handling system
  • High reproducibility
  • Adaptable to automation

Product name – Reference

PreadyPort-MDR1 (24-Multiwell)  –  KRECE-MDR01
PreadyPort-MDR1/CTRL 1:1 (24-Multiwell)  –  KRECE-MDR02
PreadyPort-MDR1 (96-Multiwell)  –  KRECE-MDR50
PreadyPort-MDR1/CTRL 1:1 (96-Multiwell)  –  KRECE-MDR51
PreadyPort-MDR1/CTRL Custom setup (96-Multiwell)  –  KRECE-MDR60
PreadyPort-CTRL (24-Multiwell)  –  KRECE-CTR01
PreadyPort-CTRL (96-Multiwell)  –  KRECE-CTR50

See also