PreadyTake MATE1

A ready-to-use system for in vitro drug transporter evaluation

  • HEK293-MATE1 (SLC47A1 gene) is expressed mainly in the apical membrane kidney and liver; and it plays an important role in drug disposition and exception mediating the efflux of diverse substrates, particularly of organic cations.
  • PreadyTake MATE1 is ready-to-use and consits of a tissue culture 96-plate seeded with transfected cells expressing MATE1 transporter as well as parental control cells.

PreadyTake MATE1 is a product manufactured in compliance with ISO 9001:2015

Applications

  • MATE1 substrate assessment for direct transport studies
  • MATE1 inhibitor assessment for drug-drug interaction studies
  • Models the net active transport event of barriers such as liver and kidney

Benefits

  • Available on demand
  • Ready-to-use without in-house cell line development or acquisition and cell propagation
  • Transportation and storage at room temperature in proprietary shipping medium
  • User friendly and easy-handling system
  • High reproducibility
  • Adaptable to automation

Product name – Reference

PreadyTake-MATE1 (96-Multiwell)  –  KRECE-MAT50
PreadyTake-MATE1/CTRL 1:1 (96-Multiwell)  –  KRECE-MAT51
PreadyTake-MATE1/CTRL Custom setup (96-Multiwell)  –  KRECE-MAT60
PreadyTake-CTRL (96-Multiwell) –  KRECE-HEK50

See also