An investigation led by the researcher Nicoló Milani was published in the prestigious analytical journal Lab on a Chip. The CacoGoblet kit was employed to investigate the permeability and the metabolism of the compound in a gut-liver-organ-on-a-chip (OoC).
The cell-based in vitro kits are shipped to South America, ensuring the quality standards. The patented biotechnology Shipping Medium® and the specialized logistic procedure at room temperature, achieve the proper delivery despite the long distances. ReadyCell is constantly growing and reaching out to more and more countries around the world.
The endothelial cells that conform the BBB limit the passage of blood circulating endogenous substrates and larger molecules to the brain. This intrinsic protective role is also a major hurdle for reasearchers developing drugs for Central Nervous System (CNS) disorders.
Evaluate intestinal inflammation with Caco2 cell-based in vitro kits to reproduce phisiological conditions.
Cell-based in vitro models are suitable to evaluate human phisiology optimizing research. This review introduce reference models to evaluate gastrointestinal metabolism.
Transmembrane efflux receptors, Pgp, MRP1 and BCRP has shown a relevant effect in the chemoterapy resistance.