Evaluating in vitro permeability with CacoReady plates was central to the study design. By quantifying the permeability of the synthesized compounds within Caco-2 cells, researchers could identify and select which compounds were best in terms of cellular adsorption.
Lourdes Gombau, head of the R&D Department, and Maria Riba, Business Development Manager, presented in the UK the last scientific article of the company, shedding light on the topic of compound intestinal toxicity.
Through this protocol we offer our CacoReady plates for assessing drug-associated gastrointestinal side effects.
Publications have confirmed the importance of developing safe chemical agents using membrane transporter analysis as a criterion. This is reflected in the field of pesticides, one of the areas in which this analysis has been most widely applied.
The main objective of this project is to develop novel 3D in vitro tools derived from the human liver, relevant to the discovery and preclinical phases of drug development.