Caco-2 based in vitro models for the screening of anti-inflammatory drugs

Caco-2 based in vitro models for the screening of anti-inflammatory drugs

Inflammatory reactions of the intestinal tract are the result of a combination of hereditary, genetic and/or environmental factors that have been clustered in the inflammatory bowel disease (IBD). ReadyCell has available CacoReady and CacoGoblet to assay compounds inflammatory properties.

A new study uses CacoGoblet in a gut-liver-organ-on-a-chip

A new study uses CacoGoblet in a gut-liver-organ-on-a-chip

An investigation led by the researcher Nicoló Milani was published in the prestigious analytical journal Lab on a Chip. The CacoGoblet kit was employed to investigate the permeability and the metabolism of the compound in a gut-liver-organ-on-a-chip (OoC).

Caco-2 Permeability Assay Protocol

Caco-2 Permeability Assay Protocol

Caco-2 cells assay is a reference assayto evaluate intestinal permeability in drug discovery stages, optimizing novel compounds screening.