Jan 27, 2022
The endothelial cells that conform the BBB limit the passage of blood circulating endogenous substrates and larger molecules to the brain. This intrinsic protective role is also a major hurdle for reasearchers developing drugs for Central Nervous System (CNS) disorders.
Sep 30, 2021
Specialized manufacturer of in vitro kits indicated to evaluate pharmacological relevant efflux and uptake receptors for TDI assays.
Jul 19, 2021
Transmembrane efflux receptors, Pgp, MRP1 and BCRP has shown a relevant effect in the chemoterapy resistance.
Jun 3, 2021
PreadyPort BCRP is a in vitro system based on transfected MDCKII cells overexpressing the BCRP transporter.
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